Safety and Outcomes of Preoperative Embolization of Intracranial Hemangioblastomas: A Systematic Review

Hemangioblastomas (HB) are benign, highly vascular tumors that comprise up to 2.5% of CNS neoplasms [1]. Common locations for these lesions include the cerebellum (44-72%), brainstem (1-6%), and spinal cord (13-44%). [2]. Most lesions arise sporadically, although nearly one-third of patients with these tumors have von Hippel-Lindau disease (VHL) [2]. There is a strong association of spinal cord HB with VHL, but lesions that arise in the cerebellum are more often sporadic [3]. The optimal treatment for symptomatic HB is surgical resection, while radiotherapy may be reserved for patients that are not surgical candidates.

Source: Clinical Neurology and Neurosurgery - September 18, 2016 Category: Neurosurgery Authors: Leonel Ampie, Winward Choy, Jonathan B. Lamano, Kartik Kesavabhotla, Rajwant Kaur, Andrew T. Parsa, Orin Bloch Source Type: research