Gastric mixed adenoneuroendocrine carcinoma: correlation of histologic characteristics with prognosis

Gastric mixed adenoneuroendocrine carcinomas (MANECs) are rare, with both the exocrine and neuroendocrine component exceeding 30% volume. Several classifications for MANECs have been proposed, yet they have not been clinically evaluated. The aim of this study was to to evaluate the correlation between tumor grade, histologic characteristics and prognosis of gastric MANECs. We collected eligible 14 cases in our series and 31 cases in the literature and compared the prognostic difference among gastric MANECs with different histologic characteristics.
Source: Annals of Diagnostic Pathology - Category: Pathology Authors: Source Type: research