The association of ACE gene polymorphism with diabetic kidney disease and renoprotective efficacy of valsartan

Conclusions:
In T2DM patients, the ACE I/D polymorphism was associated with onset of DKD. Furthermore, the ACE I/D polymorphism influenced the renoprotective response to valsartan: Patients with the DD genotype benefitted the most from this treatment.

Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - September 14, 2016 Category: Biomedical Science Authors: Wang, Y., Peng, W., Zhang, X., Qiao, H., Wang, L., Xu, Z., Wu, C. Tags: Original Article Source Type: research