Inside front cover: Comparison of anti ‐inflammatory mechanisms of mango (Mangifera Indica L.) and pomegranate (Punica Granatum L.) in a preclinical model of colitis

Mol. Nutr. Food Res. 2016, 60, 1912–1923. DOI: 10.1002/mnfr.201501008 Mango beverage (rich in gallotannins) inhibits the IGF‐1R‐AKT/mTOR axis, and pomegranate beverage (rich in ellagitannins) downregulates the mTOR downstream pathway through reduction of ERK1/2 in DSS‐treated rats. Gallic and ellagic acid are predicted in silico to bind to specific targets, such as IGF‐1R and EGFR.

http://onlinelibrary.wiley.com/resolve/doi?DOI=10.1002%2Fmnfr.201670094

Source: Nahrung / Food - September 15, 2016 Category: Nutrition Authors: Hyemee Kim, Nivedita Banerjee, Ivan Ivanov, Catherine M. Pfent, Kalan R. Prudhomme, William H. Bisson, Roderick H. Dashwood, Stephen T. Talcott, Susanne U. Mertens ‐Talcott Tags: Inside front cover Source Type: research

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