Original Research: Potential of urinary nephrin as a biomarker reflecting podocyte dysfunction in various kidney disease models

In conclusion, these results suggest that urinary nephrin-to-creatinine ratio level is a useful and reliable biomarker for predicting the amelioration of podocyte dysfunction by candidate drugs in various kidney disease models with podocyte dysfunction. This suggestion will also be validated in a clinical setting in future studies.

Source: Experimental Biology and Medicine - September 14, 2016 Category: Research Authors: Wada, Y., Abe, M., Moritani, H., Mitori, H., Kondo, M., Tanaka-Amino, K., Eguchi, M., Imasato, A., Inoki, Y., Kajiyama, H., Mimura, T., Tomura, Y. Tags: Systems Biology Source Type: research