Novokinin inhibits gastric acid secretion and protects against alcohol-induced gastric injury in rats

In this study, we found that novokinin inhibited basal gastric acid secretion and protected gastric mucosa from alcohol-induced injury in a dose-related manner in rats after intracerebroventricular (i.c.v.) administration. Novokinin significantly decreased basal gastric acid output at the dose of 50 and 100 nmol/rat.

Source: Alcohol - September 13, 2016 Category: Addiction Authors: Yang Zhang, Minghui Xiu, Jinhong Jiang, Jianzheng He, Dongqin Li, Shiwei Liang, Qiang Chen Source Type: research