Log-normal frailty models fitted as poisson generalized linear mixed models
• use a Poisson generalized linear mixed model to fit a frailty model to clustered survival data.• fix the number of pieces (baseline hazard) and explode the dataset based on the chosen pieces.• realization via %PCFrailty macro in SAS.• rule of thumb: take at least 10 events per piece.• ap proach allows more flexibility in frailty modelling.
Source: Computer Methods and Programs in Biomedicine - Category: Bioinformatics Authors: Katharina Hirsch, Andreas Wienke, Oliver Kuss Source Type: research
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