Human P[6] Rotaviruses From Sub-Saharan Africa and Southeast Asia Are Closely Related to Those of Human P[4] and P[8] Rotaviruses Circulating Worldwide

Conclusions. The observation that gene segment 4 is the main differentiator between human P[6] and non-P[6] strains suggests that the VP4 spike protein is most likely one of the main reasons preventing the rapid spread of P[6] strains to the rest of the world despite multiple introductions. These observations reinforce previous findings about the receptor specificity of P[6] rotavirus strains.

Source: The Journal of Infectious Diseases - September 12, 2016 Category: Infectious Diseases Authors: Heylen, E., Zeller, M., Ciarlet, M., Lawrence, J., Steele, D., Van Ranst, M., Matthijnssens, J. Tags: VIRUSES Source Type: research