Is vitamin E supplementation effective in reducing mortality related to cardiovascular events in people with type 2 diabetes mellitus? A systematic review

Conclusions Although, two studies showed no benefit from vitamin E supplementation, the remaining studies demonstrated that vitamin E supplementation provided cardiovascular benefits in a specific diabetic subpopulation. The study population that derived a favorable outcome from vitamin E supplementation consisted of diabetic patients with the Hp 2–2 genotype. Hence, further studies should be conducted in diabetic populations with the Hp 2–2 genotype for identifying the definitive effects of vitamin E.
Source: IJC Metabolic and Endocrine - Category: Endocrinology Source Type: research