An Open-Label, Randomized, Single-Dose, Crossover Relative Bioavailability Study of Effervescent N-Acetylcysteine Tablets versus Oral Solution N-Acetylcysteine in Fasting Healthy Adult Subjects

Conclusions Data from this study of a single dose of 11 g of oral NAC demonstrated that effervescent NAC tablets and oral solution NAC met the regulatory criteria for bioequivalence in fasting healthy adult subjects. Effervescent NAC tablets appear to be a more palatable alternative for treatment of acetaminophen overdose. ClinicalTrials.gov identifier NCT 02723669
Source: Current Therapeutic Research - Category: Drugs & Pharmacology Source Type: research