U/G SNP rs111904020 in 3 ′UTR of STAT3 regulated by miR-214 promotes hepatocellular carcinoma development in Chinese population

In conclusion, our findings have shown that the SNP rs111904020 (U/G) in STAT3 3′UTR acted as promotion factors in the HCC developm ent through disrupting the regulatory role of miR-214 in STAT3 expression.
Source: Tumor Biology - Category: Cancer & Oncology Source Type: research