Analgesic effects of adenylyl cyclase inhibitor NB001 on bone cancer pain in a mouse model

Conclusions
NB001 may serve as a novel analgesic to treat bone cancer pain. Its analgesic effect is at least partially due to the inhibition of AC1 in anterior cingulate cortex.

Source: Molecular Pain - September 8, 2016 Category: Molecular Biology Authors: Kang, W.-b., Yang, Q., Guo, Y.-y., Wang, L., Wang, D.-s., Cheng, Q., Li, X.-m., Tang, J., Zhao, J.-n., Liu, G., Zhuo, M., Zhao, M.-g. Tags: Research Article Source Type: research