High-resolution T1-relaxation time mapping displays subtle, clinically relevant, gray matter damage in long-standing multiple sclerosis

Conclusion:
Subtle GM damage was present in the cortex and thalamus of MS patients, as indicated by increased T1-RT skewness. Increased cortical skewness emerged as an independent predictor of cognitive dysfunction.

Source: Multiple Sclerosis - September 6, 2016 Category: Neurology Authors: Steenwijk, M. D., Vrenken, H., Jonkman, L. E., Daams, M., Geurts, J. J., Barkhof, F., Pouwels, P. J. Tags: Original Research Papers Source Type: research