The proportion of total C18:1 trans fatty acids in red blood cell membranes relates to carotid plaque prevalence

Consistent evidence supports the pro-atherogenic properties of dietary trans fatty acids (TFA). However, there are no clinical data on TFA intake and atheroma plaque. We cross-sectionally investigated whether the proportion of total C18:1 TFA in red blood cells (RBC), which mirrors dietary TFA intake, independently relates to carotid plaque prevalence in subjects with new-onset type 2 diabetes mellitus without prior cardiovascular disease (n=101, 56% men, mean age 61 y) and age- and sex-matched controls (n=96).

Source: The Journal of Nutritional Biochemistry - September 5, 2016 Category: Biochemistry Authors: Zoe Herreras, Montserrat Cof án, Marta Catalan, Carlos Calvo, Montserrat Pinyol, Antonio J. Amor, Rosa Gilabert, Emilio Ros, Aleix Sala-Vila, Emilio Ortega Source Type: research