Recombinant human erythropoietin improves functional recovery in patients with severe traumatic brain injury: a randomized, double blind and controlled clinical trial

Severe traumatic brain injuries including primary brain stem injury are severe forms of craniocerebral injury that are associated with a high rate of morbidity and mortality [7,10,16]. The management of severe traumatic brain injuries, in particular brain stem injuries, continues to be a challenge, as pharmacological or surgical measures are unlikely reverse the primary brain damage caused by the traumatic event. The key to clinical treatment is early and effective protection of nerve tissues to avoid secondary ischemia and hypoxia injury, in order to facilitate the recovery of nerve cells.

Source: Clinical Neurology and Neurosurgery - September 1, 2016 Category: Neurosurgery Authors: Zhong-min Li, Yi-lei Xia, Jian-xin Zhu, Feng-yang Geng, Chuan-jun Guo, Zong-lei Chong, Le-xin Wang Source Type: research