Computational discovery and in vivo validation of hnf4 as a regulatory gene in planarian regeneration

Conclusion: These results suggest that hnf4 is a regulatory gene in planarian regeneration, validate the computational predictions of the reverse-engineered dynamic model, and demonstrate the automated methodology for the discovery of novel genes, pathways and experimental phenotypes.
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Source: Bioinformatics - August 31, 2016 Category: Bioinformatics Authors: Lobo, D., Morokuma, J., Levin, M. Tags: SYSTEMS BIOLOGY Source Type: research