The Evolution of REM Sleep Behavior Disorder in Early Parkinson Disease

Conclusions:RBD increased significantly in PD patients from the de novo state to two-year follow-up. We propose RBE being named“prodromal RBD” as it may follow a continuous evolution in PD possibly similar to the spreading of Lewy bodies in PD patients. RBD itself was shown as a robust and stable marker of early PD.Citation:Sixel-Döring F, Zimmermann J, Wegener A, Mollenhauer B, Trenkwalder C. The evolution of REM sleep behavior disorder in early Parkinson disease.SLEEP 2016;39(9):1737–1742.
Source: Sleep - Category: Sleep Medicine Source Type: research