Patterns and Predictors of Freezing of Gait Improvement Following Rasagiline Therapy: A Pilot Study

In Parkinson ’s disease (PD), health related quality of life is impacted negatively by progressive gait disturbances [1]. Gait impairments in PD lead to increased falls and reduced community mobility [2,3]. One of the more disabling gait impairments associated with PD is freezing of gait (FoG). FoG is characte rized by the sudden inability to voluntarily initiate stepping movements [4]. While FoG is more commonly associated with advanced stages of the disease, it can occur at any stage and can present substantial challenges in the clinical management of gait impairment in PD.
Source: Clinical Neurology and Neurosurgery - Category: Neurosurgery Authors: Source Type: research