Changes in synaptic transmission of substantia gelatinosa neurons after spinal cord hemisection revealed by analysis using in vivo patch-clamp recording

Conclusions These suggest that substantia gelatinosa neurons receive tonic inhibition by spinal inhibitory interneurons which generate persistent action potentials. Spinal hemisection results in hyperexcitation of substantia gelatinosa neurons at least in part by eliminating the tonic descending control of spinal inhibitory interneurons from supraspinal levels.

http://mpx.sagepub.com/cgi/content/abstract/12/0/1744806916665827?rss=1

Source: Molecular Pain - August 27, 2016 Category: Molecular Biology Authors: Kozuka, Y., Kawamata, M., Furue, H., Ishida, T., Tanaka, S., Namiki, A., Yamakage, M. Tags: Research Article Source Type: research