Adeno ‐associated virus‐mediated colonic secretory expression of HMGB1 A box attenuates experimental colitis in mice

ConclusionsIntracolonic application of AAV‐HMGB1 A box is effective in alleviating murine colitis and has therapeutic potential in human IBDs.

Source: The Journal of Gene Medicine - July 31, 2016 Category: Genetics & Stem Cells Authors: Xiaoyan Zheng, Yifei Lv, Shuang Li, Qiannan Zhang, Xueting Zhang, Zhiming Hao Tags: RESEARCH ARTICLE Source Type: research