EGR-1 Is an Active Transcription Factor in TGF- β2 Mediated Small Intestinal Cell Differentiation

In this study, IEC-6 (rat intestinal epithelial cells) cells were used as a model to study cell differentiation mediated by transforming growth factor- β2 (TGF-β2), the most abundant growth factor in human milk. We focused on the transcription factor early growth response 1 (EGR-1), as we found a robust and rapid response in our initial transcription factor screen.
Source: The Journal of Nutritional Biochemistry - Category: Biochemistry Authors: Source Type: research