Enhancement of Pathologist's Routine Practice: Reuse of DNA Extracted from Immunostained Formalin-fixed Paraffin-embedded (FFPE) Slides in Downstream Molecular Analysis of Cancer

Conclusion: This study is a proof of concept to recycle and reuse DNA from IHC stained slides with suitable concentration and integrity for further downstream molecular applications. These findings will enhance the pathologists' knowledge, attitudes and practices (KAP) towards the use of these biospecimens and support the implementation of this approach in clinical pathology practice. Therefore, the scientific community will benefit from the largest comprehensive database of human fully annotated FFPE biospecimens already available at their disposal in order to demystify the complexity and the heterogeneity of many challenging diseases and foster the transition towards precision medicine.

Source: Cancer Genomics and Proteomics - August 25, 2016 Category: Cancer & Oncology Authors: AL-ATTAS, A., ASSIDI, M., AL-MAGHRABI, J., DALLOL, A., SCHULTEN, H.-J., ABU-ELMAGD, M., CHAUDHARY, A., ABUZENADAH, A., BUDOWLE, B., BUHMEIDA, A., AL-QAHTANI, M. Tags: Article Source Type: research