Melatonin controlled apoptosis and protected the testes and sperm quality against bisphenol A-induced oxidative toxicity

In conclusion, melatonin protected against BPA-induced apoptosis by controlling Bcl-2 expression and ameliorating oxidative stress in the testes and sperm. Thus, melatonin is a promising pharmacological agent for preventing the potential reproductive toxicity of BPA following occupational or environmental exposures.

Source: Toxicology and Industrial Health - August 24, 2016 Category: Toxicology Authors: Othman, A. I., Edrees, G. M., El-Missiry, M. A., Ali, D. A., Aboel-Nour, M., Dabdoub, B. R. Tags: Articles Source Type: research