Immunostaining of Bcl-2 and HER2/neu in urinary bladder carcinoma

Conclusion: Expression of Bcl-2 in the bladder carcinoma seems to be associated with a less aggressive phenotype and does not play an important role in tumour progression. These findings support the role of HER2/neu in the carcinogenesis of urinary bladder carcinoma regarding behavior and aggressiveness, and thus HER2/neu could be considered as a poor prognostic parameter in urinary bladder carcinoma.
Source: Egyptian Journal of Pathology - Category: Pathology Tags: Original Articles Source Type: research