Comparative virulence of in vitro ‐cultured primate‐ and pig‐associated Helicobacter suis strains in a BALB/c mouse and a Mongolian gerbil model

ConclusionsApart from the cynomolgus monkey‐associated strain which was unable of colonizing the stomach of Mongolian gerbils, no substantial differences in virulence were found in rodent models between in vitro‐cultured pig‐associated, cynomolgus monkey‐associated and rhesus monkey‐associated H. suis strains. The experimental host determines the outcome of the immune response against H. suis infection, rather than the original host.

Source: Helicobacter - August 25, 2016 Category: Gastroenterology Authors: Iris Bosschem, Bram Flahou, Jaco Bakker, Edwin Heuvelman, Jan A.M. Langermans, Ellen De Bruyne, Myrthe Joosten, Annemieke Smet, Richard Ducatelle, Freddy Haesebrouck Tags: Original Article Source Type: research