Discriminating self from non-self in nucleic acid sensing

Nature Reviews Immunology 16, 566 (2016). doi:10.1038/nri.2016.78 Authors: Martin Schlee & Gunther Hartmann Innate immunity against pathogens relies on an array of immune receptors to detect molecular patterns that are characteristic of the pathogens, including receptors that are specialized in the detection of foreign nucleic acids. In vertebrates, nucleic acid sensing is the dominant antiviral defence pathway. Stimulation
Source: Nature Reviews Immunology - Category: Allergy & Immunology Authors: Tags: Review Source Type: research