The stress protein heat shock cognate 70 (Hsc70) inhibits the Transient Receptor Potential Vanilloid type 1 (TRPV1) channel

Conclusions Our work identified Hsc70 and its ATPase activity as a central cofactor of TRPV1 channel function and points to the role of this stress protein in pain associated with neurodegenerative and/or metabolic disorders, including aging.

http://mpx.sagepub.com/cgi/content/abstract/12/0/1744806916663945?rss=1

Source: Molecular Pain - August 23, 2016 Category: Molecular Biology Authors: Iftinca, M., Flynn, R., Basso, L., Melo, H., Aboushousha, R., Taylor, L., Altier, C. Tags: Research Article Source Type: research