Protease Inhibitor Resistance in the First 3 Years of Second-Line Antiretroviral Therapy for HIV-1 in Sub-Saharan Africa

Conclusions. Although VL suppression rates were high, PI resistance was detected in 22% of participants with VLs ≥1000 cps/mL. To ensure long-term ART success, intensified support for adherence, VL and drug resistance testing, and third-line drugs will be necessary.

Source: The Journal of Infectious Diseases - August 23, 2016 Category: Infectious Diseases Authors: Boender, T. S., Hamers, R. L., Ondoa, P., Wellington, M., Chimbetete, C., Siwale, M., Labib Maksimos, E. E. F., Balinda, S. N., Kityo, C. M., Adeyemo, T. A., Akanmu, A. S., Mandaliya, K., Botes, M. E., Stevens, W., Rinke de Wit, T. F., Sigaloff, K. C. E. Tags: HIV/AIDS Source Type: research