Plasma ESR1 Mutations and the Treatment of Estrogen Receptor-Positive Advanced Breast Cancer [Rapid Communication]

Conclusion
ESR1 mutation analysis in plasma after progression after prior AI therapy may help direct choice of further endocrine-based therapy. Additional confirmatory studies are required.

Source: Journal of Clinical Oncology - August 23, 2016 Category: Cancer & Oncology Authors: Fribbens, OLeary, Kilburn, Hrebien, Garcia-Murillas, Beaney, Cristofanilli, Andre, Loi, Loibl, Jiang, Bartlett, Koehler, Dowsett, Bliss, Johnston, Turner Tags: Combined Modality, Hormonal Therapy, Translational Oncology, Rapid Communications Source Type: research