Hereditary breast and ovarian cancer: new genes in confined pathways

Nature Reviews Cancer 16, 599 (2016). doi:10.1038/nrc.2016.72 Authors: Finn Cilius Nielsen, Thomas van Overeem Hansen & Claus Storgaard Sørensen Genetic abnormalities in the DNA repair genes BRCA1 and BRCA2 predispose to hereditary breast and ovarian cancer (HBOC). However, only approximately 25% of cases of HBOC can be ascribed to BRCA1 and BRCA2 mutations. Recently, exome sequencing has uncovered substantial locus

http://feeds.nature.com/~r/nrc/rss/current/~3/9Xhg_Pqs-oA/nrc.2016.72

Source: Nature Reviews Cancer - August 11, 2016 Category: Cancer & Oncology Authors: Finn Cilius Nielsen Thomas van Overeem Hansen Claus Storgaard S ørensen Tags: Review Source Type: research