Engineered T cells: the promise and challenges of cancer immunotherapy

Nature Reviews Cancer 16, 566 (2016). doi:10.1038/nrc.2016.97 Authors: Andrew D. Fesnak, Carl H. June & Bruce L. Levine The immune system evolved to distinguish non-self from self to protect the organism. As cancer is derived from our own cells, immune responses to dysregulated cell growth present a unique challenge. This is compounded by mechanisms of immune evasion and immunosuppression that develop in the
Source: Nature Reviews Cancer - Category: Cancer & Oncology Authors: Tags: Review Source Type: research