Pancreatic cancer biology and genetics from an evolutionary perspective

Nature Reviews Cancer 16, 553 (2016). doi:10.1038/nrc.2016.66 Authors: Alvin Makohon-Moore & Christine A. Iacobuzio-Donahue Cancer is an evolutionary disease, containing the hallmarks of an asexually reproducing unicellular organism subject to evolutionary paradigms. Pancreatic ductal adenocarcinoma (hereafter referred to as pancreatic cancer) is a particularly robust example of this phenomenon. Genomic features indicate that pancreatic cancer cells are selected for
Source: Nature Reviews Cancer - Category: Cancer & Oncology Authors: Tags: Review Source Type: research