Targeting of vascular cell adhesion molecule-1 by 18F-labelled nanobodies for PET/CT imaging of inflamed atherosclerotic plaques

Conclusion
The [18F]-FB-anti-VCAM-1 Nb, cross-reactive for both mouse and human VCAM-1, allows non-invasive PET/CT imaging of VCAM-1 expression in atherosclerotic plaques in a murine model and may represent an attractive tool for imaging vulnerable atherosclerotic plaques in patients.

Source: European Journal of Echocardiography - August 21, 2016 Category: Cardiology Authors: Bala, G., Blykers, A., Xavier, C., Descamps, B., Broisat, A., Ghezzi, C., Fagret, D., Van Camp, G., Caveliers, V., Vanhove, C., Lahoutte, T., Droogmans, S., Cosyns, B., Devoogdt, N., Hernot, S. Tags: ORIGINAL ARTICLES Source Type: research