Tight junctions: from simple barriers to multifunctional molecular gates
Nature Reviews Molecular Cell Biology 17, 564 (2016).
doi:10.1038/nrm.2016.80
Authors: Ceniz Zihni, Clare Mills, Karl Matter & Maria S. Balda
Epithelia and endothelia separate different tissue compartments and protect multicellular organisms from the outside world. This requires the formation of tight junctions, selective gates that control paracellular diffusion of ions and solutes. Tight junctions also form the border between the apical and basolateral plasma-membrane domains
Source: Nature Reviews Molecular Cell Biology - Category: Cytology Authors: Ceniz Zihni Clare Mills Karl Matter Maria S. Balda Tags: Review Source Type: research