RNA decay: The exosome TRAMPs on viral RNA

Nature Reviews Molecular Cell Biology 17, 534 (2016). doi:10.1038/nrm.2016.113 Author: Eytan Zlotorynski Performing RNAi screens for factors that restrict several RNA viruses in fruit flies, Molleston et al. discovered that depletion of the 3′ to 5′ exonucleases dRrp6 or dDis3, which are the catalytic subunits of the RNA exosome complex, or depletion of dMtr4 or dZcchc7,
Source: Nature Reviews Molecular Cell Biology - Category: Cytology Authors: Tags: Research Highlight Source Type: research