Mechanotransduction: May the force be with you

Nature Reviews Molecular Cell Biology 17, 533 (2016). doi:10.1038/nrm.2016.105 Author: Paulina Strzyz Mechanical strain, transmitted by the remodelling of the actomyosin cytoskeleton and concomitant depletion of the nuclear actin pool, is shown to induce silencing of differentiation genes in epidermal stem cells, linking mechanical cues to the genetic regulation of cell fate.

http://feeds.nature.com/~r/nrm/rss/current/~3/CAqRETsjd10/nrm.2016.105

Source: Nature Reviews Molecular Cell Biology - July 26, 2016 Category: Cytology Authors: Paulina Strzyz Tags: Research Highlight Source Type: research