Carbonic Anhydrase Inhibitors Reduce Cardiac Dysfunction after Sustained Coronary Artery Ligation in Rats

Two potent carbonic anhydrase (CA) inhibitors with widely differing membrane permeability, poorly diffusible benzolamide (BZ) and highly diffusible ethoxzolamide (ETZ) were assessed to determine whether they can reduce cardiac dysfunction in rats subjected to coronary artery ligation (CAL)-induced myocardial infarction.

Source: Cardiovascular Pathology - August 20, 2016 Category: Cardiology Authors: Lorena A. Vargas, Oscar A. Pinilla, Romina G. D íaz, Diana E. Sepúlveda, Erik R. Swenson, Néstor G. Pérez, Bernardo V. Álvarez Source Type: research