A single alcohol drinking session is sufficient to enable subsequent aversion-resistant consumption in mice

Addiction is mediated in large part by pathological motivation for rewarding, addictive substances, and alcohol-use disorders (AUDs) continue to extract a very high physical and economic toll on society despite extensive efforts directed toward treatment of these disorders. Compulsive alcohol drinking, where intake continues despite negative consequences, is considered a particular obstacle during treatment of AUDs. Aversion-resistant drives for alcohol have been modeled in rodents, where animals continue to consume even when alcohol is adulterated with the bitter tastant quinine, or is paired with another aversive consequence.
Source: Alcohol - Category: Addiction Authors: Source Type: research
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