Paraffin Processing of Stented Arteries Using a Post-Fixation Dissolution of Metallic and Polymeric Stents

Studying the morphology of the arterial response to endovascular stent implantation, requires embedding the explanted stented artery in rigid materials such as poly (methyl methacrylate) to enable sectioning through both the in situ stent and the arterial wall, thus maintaining the proper anatomic relationships. This is a laborious, time consuming process. Moreover, the technical quality of stained plastic sections is typically suboptimal, and in some cases precludes immunohistochemical analysis.

Source: Cardiovascular Pathology - August 20, 2016 Category: Cardiology Authors: Ilia Fishbein, Tre Welch, David T. Guerrero, Ivan S. Alferiev, Richard F. Adamo, Michael Chorny, Rohit K. Gupte, Yanqing Tang, Robert J. Levy Source Type: research