Gallium-68 EDTA PET/CT for Renal Imaging

Nuclear medicine renal imaging provides important functional data to assist in the diagnosis and management of patients with a variety of renal disorders. Physiologically stable metal chelates like ethylenediaminetetraacetic acid (EDTA) and diethylenetriamine penta-acetate (DTPA) are excreted by glomerular filtration and have been radiolabelled with a variety of isotopes for imaging glomerular filtration and quantitative assessment of glomerular filtration rate. Gallium-68 (68Ga) EDTA PET usage predates Technetium-99m (99mTc) renal imaging, but virtually disappeared with the widespread adoption of gamma camera technology that was not optimal for imaging positron decay.
Source: Seminars in Nuclear Medicine - Category: Nuclear Medicine Authors: Source Type: research