Atlas-Based Ventricular Shape Analysis for Understanding Congenital Heart Disease

Congenital heart disease is associated with abnormal ventricular shape that can affect wall mechanics and may be predictive of long-term adverse outcomes. Atlas-based parametric shape analysis was used to analyze ventricular geometries of eight adolescent or adult single-ventricle CHD patients with tricuspid atresia and Fontans. These patients were compared with an “atlas” of non-congenital asymptomatic volunteers, resulting in a set of z-scores which quantify deviations from the control population distribution on a patient-by-patient basis.

Source: Progress in Pediatric Cardiology - August 17, 2016 Category: Cardiology Authors: Genevieve Farrar, Avan Suinesiaputra, Kathleen Gilbert, James C. Perry, Sanjeet Hegde, Alison Marsden, Alistair A. Young, Jeffrey H. Omens, Andrew D. McCulloch Tags: Review Source Type: research