Helicobacter pylori in children

Abstract Helicobacter pylori infection in early childhood may differ in many aspects compared to infection in adulthood: the immune response in the gut, the type and prevalence of complications within and outside the stomach, and the impact on long‐term health. In high prevalence countries, transient infections seem to be common in infants and toddlers, and the consequences of this phenomenon on the short‐ and long‐term immune response are still unclear. Other controversial issues are related to the question of which H. pylori‐infected children benefit from treatment and which is the best regimen to eradicate the infection in the presence of a worldwide increasing antibiotic resistance. The first large‐scale randomized placebo‐controlled vaccination trial in schoolchildren indicates that prevention of the infection may be possible.
Source: Helicobacter - Category: Gastroenterology Authors: Tags: Original Article Source Type: research