Prostaglandin E2 Reduces Cardiac Contractility via EP3 Receptor [Original Article]

Conclusions—
Contractility is reduced via the EP3 receptor but increased via EP4. These effects may be mediated through changes in phospholamban phosphorylation and has relevance to detrimental effects of inflammation.

Source: Circulation: Heart Failure - August 7, 2016 Category: Cardiology Authors: Gu, X., Xu, J., Zhu, L., Bryson, T., Yang, X.-P., Peterson, E., Harding, P. Tags: Contractile Function, Growth Factors/Cytokines, Inflammation, Heart Failure Original Article Source Type: research