Hypochloremia, Diuretic Resistance, and Outcome in Patients With Acute Heart Failure [Original Article]

Conclusions—
Low serum chloride at AHF hospital admission was strongly associated with impaired decongestion. New or persistent hypochloremia 14 days later was independently associated with reduced survival, whereas hypochloremia that resolved by day 14 was not.

Clinical Trial Registration—
URL: http://www.clinicaltrials.gov. Unique identifier: NCT00354458.

Source: Circulation: Heart Failure - August 8, 2016 Category: Cardiology Authors: ter Maaten, J. M., Damman, K., Hanberg, J. S., Givertz, M. M., Metra, M., OConnor, C. M., Teerlink, J. R., Ponikowski, P., Cotter, G., Davison, B., Cleland, J. G., Bloomfield, D. M., Hillege, H. L., van Veldhuisen, D. J., Voors, A. A., Testani, J. M. Tags: Heart Failure Original Article Source Type: research