Novel oral anticoagulants for the secondary prevention of cerebral ischemia: a network meta-analysis

Conclusions:
The three NOACs showed differences in terms of safety and efficacy for secondary stroke prevention in NVAF. Our findings can serve only as hypothesis generation and require independent confirmation in head-to-head RCTs, owing to the sparse available evidence and increased uncertainty in both indirect effect estimates and ranking of treatments.

Source: Therapeutic Advances in Neurological Disorders - August 14, 2016 Category: Neurology Authors: Katsanos, A. H., Mavridis, D., Parissis, J., Deftereos, S., Frogoudaki, A., Vrettou, A.-R., Ikonomidis, I., Chondrogianni, M., Safouris, A., Filippatou, A., Voumvourakis, K., Triantafyllou, N., Ellul, J., Karapanayiotides, T., Giannopoulos, S., Alexandrov Tags: Original Research Source Type: research