Phase II Multicenter, Randomized, Double-Blind Controlled Study of Efficacy and Safety of Umbilical Cord-Derived Mesenchymal Stromal Cells in the Prophylaxis of Chronic Graft-Versus-Host Disease After HLA-Haploidentical Stem-Cell Transplantation [Hematologic Malignancy]

Conclusion
Our findings suggest that the repeated infusion of MSCs might inhibit cGVHD symptoms in patients after HLA-haplo HSCT, accompanied by changes in the numbers and subtypes of T, B, and NK cells, leading to the acquisition of immune tolerance.

Source: Journal of Clinical Oncology - August 14, 2016 Category: Cancer & Oncology Authors: Gao, Zhang, Hu, Liu, Kong, Lou, Su, Yang, Li, Liu, Zhang, Gao, Zhu, Wen, Wang, Chen, Zhong, Zhang Tags: Leukemia, Combined Therapy, Biological Therapy Hematologic Malignancy Source Type: research