Past  Decline Versus Current eGFR and Subsequent Mortality Risk

This is an individual-level meta-analysis of the risk of mortality associated with antecedent eGFR slope among 1.2 million subjects within the CKD Prognosis Consortium. Over a 3-year antecedent period, compared with a slope of 0 ml/min per 1.73 m(2) per year, a slope of -6 ml/min per 1.73 m(2) per year was associated with adjusted hazard ratios for all-cause mortality of 1.25 (95% confidence interval [95% CI], 1.09 to 1.44) among CKD cohorts and 1.15 (95% CI, 1.01 to 1.31) among other cohorts during a follow-up of 3.2 years. Results were similar for cardiovascular and non cardiovascular causes of death and stronger for longer antecedent periods.   : Past Decline Versus Current eGFR and Subsequent ESRD Risk Bariatric surgery is associated with improvement in kidney outcomes Comparison of Risk Prediction Using the CKD-EPI Equation and the MDRD Study Equation for Estimated Glomerular Filtration Rate
Source: Nephrology Now - Category: Urology & Nephrology Authors: Tags: Chronic Kidney Disease Clinical Nephrology Clinical Trial Results Source Type: research