TCF-1 participates in the occurrence of dedifferentiated chondrosarcoma

In conclusion, this study proved that TCF-1 participates in the dedifferentiation of DDCS, which may be mediated byrunx2 gene andsox9 gene. Also, TCF-1 can be of important prognostic value and a promising therapeutic target for DDCS patients.
Source: Tumor Biology - Category: Cancer & Oncology Source Type: research