Clonidine and ketamine for stable hemodynamics in off-pump coronary artery bypass
Conclusions
Combined low-dose clonidine and ketamine produced perioperative sedation and effective suppression of sympathetic response with stable hemodynamics. Intraoperative beta-blocker use was reduced without increasing inotrope requirement. This combination prolonged the analgesic effect of opioids, reducing postoperative pain score and analgesic requirement. Low-dose clonidine alone produced sedation but did not completely block sympathetic response. Intensive care unit stay and patient outcome were not affected by clonidine or ketamine.
Source: Asian Cardiovascular and Thoracic Annals - Category: Cardiology Authors: Patel, J., Thosani, R., Kothari, J., Garg, P., Pandya, H. Tags: Cardiac Source Type: research
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