Magnetic nanoparticles and blood flow behavior in non-Newtonian pulsating flow within the carotid artery in drug delivery application

This article is devoted to study on the magnetic drug targeting technique by particle tracking in the presence of a magnetic field in the carotid artery. The results showed that applying a magnetic field on the secondary branch of the external carotid artery in a pulsating non-Newtonian flow drove nanoparticles inside this sub-branch, while none of them entered that branch in the absence of magnetic field on the internal carotid artery. Wall shear stress distributions showed that high shear stress occurs near the bifurcation region, and its maximum value belongs to the junction of internal carotid artery and external carotid artery.
Source: Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine - Category: Biomedical Engineering Authors: Tags: Original Articles Source Type: research